Sage Therapeutics Layoffs 2025. Both the layoffs and executive leadership shifts are aimed at helping to reduce sage’s operating expenses and strengthen its balance sheet, the company said. Sage is evaluating next steps, if any, for other potential indications.

By the end of the year, the biotech will lay off at least 165 employees, including 55% of the r&d workforce, along with amy schacterle, ph.d.,. A drug developer is cutting more than a dozen employees in raleigh, part of more than 150 layoffs companywide.